What is the test for a patent for a prediction?

A sound prediction must meet four criteria. First, there must be a factual basis for the prediction. Second, the inventor must have an articulable and sound line of reasoning from the factual basis to the desired outcome. Third, the inventor must set out in the patent the factual basis and the line of reasoning he or she was applying. Fourth, of course, the predicted outcome must be borne out by subsequent testing. An incorrect prediction cannot be a sound one. (See Apotex v. Wellcome, above, at para. 70, 76.) (i) Olanzapine vs. flumezapine – liver enzymes